Bromine → 1-Bromo-1-(2,4-dichlorophenoxy)-3,3-dimethyl-4-fluoro-2-butanone
反応式
[Cl:1][C:2]1[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:3]=1[O:4][CH2:5][C:6](=[O:12])[C:7]([CH3:11])([CH3:10])[CH2:8][F:9].[Br:18]Br>C(Cl)(Cl)Cl>[Br:18][CH:5]([O:4][C:3]1[CH:13]=[CH:14][C:15]([Cl:17])=[CH:16][C:2]=1[Cl:1])[C:6](=[O:12])[C:7]([CH3:11])([CH3:10])[CH2:8][F:9]参加物
4
実験手順
244.6 g (0.88 mol) of crude 1-(2,4-dichloro-phenoxy)-3,3-dimethyl-4-fluoro-2-butanone were dissolved in 700 ml of chloroform, and 46 ml of bromine were added dropwise at 30° C. at a rate such that decolorization continuously occurred. When the addition had ended, the mixture was subsequently stirred for 30 minutes and then concentrated by distilling off the chloroform in vacuo. 315 g (100% of theory) of 1-bromo-1-(2,4-dichlorophenoxy)-3,3-dimethyl-4-fluoro-2-butanone were obtained as a viscous oil which could be further reacted in crude form.