benzyl (2S,3R)-3-cyclopropyl-2-ethyl-3-hydroxypyrrolidine-1-carboxylate → (2S,3R)-3-cyclopropyl-2-ethylpyrrolidin-3-ol
反応式
[CH:1]1([C@:4]2([OH:21])[CH2:8][CH2:7][N:6](C(OCC3C=CC=CC=3)=O)[C@H:5]2[CH2:19][CH3:20])[CH2:3][CH2:2]1>[Pd].O>[CH:1]1([C@:4]2([OH:21])[CH2:8][CH2:7][NH:6][C@H:5]2[CH2:19][CH3:20])[CH2:3][CH2:2]1参加物
4
実験手順
By an operation in the same manner as in Reference Example 4 and using benzyl (2S,3R)-3-cyclopropyl-2-ethyl-3-hydroxypyrrolidine-1-carboxylate (2.01 g) and 50% water containing-10% Pd/C (0.20 g), the title compound was obtained as a colorless solid (yield: 1.35 g, yield: 96%).
出典と根拠
- ORDレコード
- ord-48273e646f5e4254adbad3d003064ed4
- 出典データセット
- uspto-grants-2011_09
- 特許番号
- US08013008B2
反応ノート
読み込み中…