Trifluoroacetic acid → HCID 67388278、化合物
反応式
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[C:19]([O:20][CH2:21][C:22]3[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=3)=[CH:18][CH:17]=[CH:16][N:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31]>ClCCl>[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31].[N:25]1[CH:26]=[CH:27][C:22]([CH2:21][O:20][C:19]2[C:14]([N:11]3[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]3)=[N:15][CH:16]=[CH:17][CH:18]=2)=[CH:23][CH:24]=1参加物
4
実験手順
The crude 4-[3-(Pyridin-4-ylmethoxy)-pyridin-2-yl]piperazine-1-carboxylic acid tert-butyl ester (˜500 mg) was dissolved in 10 mL of 30% trifluoroacetic acid in dichloromethane. The reaction mixture was stirred for 3 hr and then the solvent was removed under vacuum. The impure material was used without purification.