Trifluoroacetic acid → HCID 59366526、化合物

HRID 908656ノート

反応式

HRID 908656 の反応式
[Cl:1][C:2]([Cl:23])=[CH:3][CH2:4][O:5][C:6]1[CH:20]=[C:19]([Cl:21])[C:9]([O:10][CH2:11][C:12]([O:14]C(C)(C)C)=[O:13])=[C:8]([Cl:22])[CH:7]=1.FC(F)(F)C(O)=O>C(Cl)Cl>[Cl:23][C:2]([Cl:1])=[CH:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([Cl:22])[C:9]([O:10][CH2:11][C:12]([OH:14])=[O:13])=[C:19]([Cl:21])[CH:20]=1

参加物

4

反応物 2

HCID 6422Trifluoroacetic acidHCID 59366522Tert-butyl 2-(4-(3,3-dichloroprop-2-enyloxy)-2,6-dichlorophenoxy)acetate

生成物 1

HCID 59366526HCID 59366526、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

反応条件

温度
0 °C

実験手順

A mixture of 0.3 gram (0.0008 mole) of tert-butyl 2-(4-(3,3-dichloroprop-2-enyloxy)-2,6-dichlorophenoxy)acetate in 3.0 mL of methylene chloride was stirred and cooled to 0° C. Trifluoroacetic acid (3.0 mL, 0.04 mole) was added and the reaction mixture was allowed to warm to ambient temperature where it stirred for two hours. The reaction mixture was concentrated under reduced pressure leaving a residue. The residue was dissolved in methylene chloride and the solution concentrated under reduced pressure and the resulting residue was dissolved in methylene chloride again. The solution was concentrated under reduced pressure to yield a quantitative amount of the subject compound as a white powder.

後処理

  1. temperatureto warm to ambient temperature where it
  2. stirringstirred for two hours
  3. concentrationThe reaction mixture was concentrated under reduced pressure
  4. customleaving a residue
  5. concentrationthe solution concentrated under reduced pressure
  6. dissolutionthe resulting residue was dissolved in methylene chloride again
  7. concentrationThe solution was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-7c60a271ea024946a3ffb269a31a06e4
出典データセット
uspto-grants-2011_09
特許番号
US08017635B2

反応ノート

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