Hydrogen Peroxide → Dibenzothiophene sulfoxide

HRID 909986

反応式

HRID 909986 の反応式
[CH:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[S:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[OH:14]O.O>FC(F)(F)C(O)=O>[CH:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[S:6](=[O:14])[C:5]=2[CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 3023Dibenzothiophene

生成物 1

HCID 13898Dibenzothiophene sulfoxide

試薬・触媒・溶媒 1

HCID 6422Trifluoroacetic acid溶媒

反応条件

温度
60 °C

実験手順

Dibenzothiophene (20.0 g) is suspended in 80.0 ml of trifluoroacetic acid at room temperature. To the suspension is slowly dropped 12.4 ml of 30% aqueous hydrogen peroxide while cooling with ice so as to maintain the reaction temperature around 60° C. After completion of dropping, the reaction solution is stirred at room temperature for 30 minutes. After the reaction, the reaction solution is added to 1,000 ml of water to precipitate crystals. The crystals are recovered by filtration and washed with water. The obtained crystals are recrystallized with acetonitrile to obtain 19.2 g of dibenzothiophene-S-oxide.

後処理

  1. temperaturewhile cooling with ice so as
  2. customAfter the reaction
  3. customto precipitate crystals
  4. filtrationThe crystals are recovered by filtration
  5. washwashed with water
  6. customThe obtained crystals are recrystallized with acetonitrile

出典と根拠

ORDレコード
ord-9216a22ca85c497ea02407fad91d4517
出典データセット
uspto-grants-2011_09
特許番号
US08021819B2

関連ノート

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