反応式
O[CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[N:5]=1)[CH3:3].S(Cl)([Cl:13])=O>C(Cl)Cl>[ClH:13].[Cl:13][CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[N:5]=1)[CH3:3]参加物
4
実験手順
To the crude 2-(1-hydroxyethyl)-6-methylpyridine (1.6 g, 11.7 mmol) in dry DCM (15 mL) add with stirring thionyl chloride (2.0 mL, 27 mmol) and continue stirring overnight Concentrate in vacuo, azeotrope three times with dry chloroform and dry under high vacuum to provide the title compound as a tan solid (1.9 g, 85%). MS (APCI+) m/z 156 (M+H)+.
後処理
- concentrationConcentrate in vacuo
- customdry under high vacuum
出典と根拠
- ORDレコード
- ord-a65254b7cd5c4aea8e7be1512f5c8d13
- 出典データセット
- uspto-grants-2011_09
- 特許番号
- US08022062B2
関連ノート
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