Hydrazine hydrate (1:1) → 2-{4-[2-(3-Fluoro-pyridin-2-yl)-imidazol-1-ylmethyl]-6-hydrazino-pyrimidin-5-yl}-ethanol
反応式
Cl[C:2]1[C:7]([CH2:8][CH2:9][O:10]C(=O)C)=[C:6]([CH2:14][N:15]2[CH:19]=[CH:18][N:17]=[C:16]2[C:20]2[C:25]([F:26])=[CH:24][CH:23]=[CH:22][N:21]=2)[N:5]=[CH:4][N:3]=1.O.[NH2:28][NH2:29]>CCO>[F:26][C:25]1[C:20]([C:16]2[N:15]([CH2:14][C:6]3[C:7]([CH2:8][CH2:9][OH:10])=[C:2]([NH:28][NH2:29])[N:3]=[CH:4][N:5]=3)[CH:19]=[CH:18][N:17]=2)=[N:21][CH:22]=[CH:23][CH:24]=1参加物
4
反応条件
- 温度
- 70 °C