Dichloromethane → HCID 178513167、化合物
反応式
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].C(=O)(O)O.[NH:15]([C:17](=[NH:19])[NH2:18])[NH2:16].ClCCl>N1C=CC=CC=1>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:16][NH:15][C:17](=[NH:18])[NH2:19])=[O:5]参加物
5
反応条件
- 温度
- 25 °C
実験手順
A mixture of 2-chlorobenzoyl chloride (10 g, 60 mmol, 1.00 equiv) and hydrazinecarboximidamide carbonic acid salt (11.6 g, 85 mmol, 1.49 equiv) in pyridine (10 mL) and dichloromethane (100 g, 1.18 mol, 41.21 equiv) was stirred for 3 h at 25° C. After the reaction was completed, the resulting mixture was concentrated under vacuum. The residue was purified via silica gel column (ethyl acetate/petroleum ether (10/1)) resulting in 3 g (22%) of 2-(2-chlorobenzoyl)hydrazinecarboximidamide as yellow oil.
後処理
- concentrationthe resulting mixture was concentrated under vacuum
- customThe residue was purified via silica gel column (ethyl acetate/petroleum ether (10/1))
- customresulting in 3 g (22%) of 2-(2-chlorobenzoyl)hydrazinecarboximidamide as yellow oil
出典と根拠
- ORDレコード
- ord-7aeec9edd08a412a918a756812d79df1
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09278973B2
反応ノート
読み込み中…