Chlorodiisopropylphosphine → HCID 178425660、化合物

HRID 925034

反応式

HRID 925034 の反応式
[CH3:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]([NH:8][C:9]2[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:16])=[NH:7])=[CH:4][CH:3]=1.C([Li])CCC.Cl[P:25]([CH:29]([CH3:31])[CH3:30])[CH:26]([CH3:28])[CH3:27]>>[CH:26]([P:25]([CH:29]([CH3:31])[CH3:30])[N:7]=[C:6]([NH:8][C:9]1[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:16])[C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:18][CH:17]=1)([CH3:28])[CH3:27]

参加物

4

反応物 3

HCID 538967ChlorodiisopropylphosphineHCID 178418339ButyllithiumHCID 178425630HCID 178425630、化合物

生成物 1

HCID 178425660HCID 178425660、化合物

実験手順

Procedure as described for NP Amidine I using the following amounts: 1.19 g of 4-methyl-N1-(2,6-dimethylphenyl)benzamidine (Amidine III, 5.0 mmol), 2.50 mL of 2.0 M butyllithium (5.0 mmol), 0.80 mL chlorodiisopropylphosphine (5.0 mmol). After filtration to remove lithium chloride and removal of solvent, a yellow oil was isolated (1.76 g).

後処理

  1. filtrationAfter filtration
  2. customto remove
  3. customlithium chloride and removal of solvent
  4. customa yellow oil was isolated (1.76 g)

出典と根拠

ORDレコード
ord-7e05587c55fe4a859af7cc6655129a71
出典データセット
uspto-grants-2016_03
特許番号
US09283555B2

関連ノート

読み込み中…