HCID 90042500、化合物 → (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diamine
反応式
[N:1]([C@@H:4]1[CH2:8][O:7][C@@H:6]2[C@@H:9]([N:12]=[N+]=[N-])[CH2:10][O:11][C@H:5]12)=[N+]=[N-]>CO.[Pd]>[O:7]1[CH2:8][C@@H:4]([NH2:1])[C@H:5]2[O:11][CH2:10][C@H:9]([NH2:12])[C@@H:6]12参加物
4
実験手順
A mixture of (3R,3aR,6S,6aR)-3,6-diazidohexahydrofuro[3,2-b]furan (2.5 g, 12.74 mmol) and 5% palladium on active carbon (0.25 g) in methanol (300 mL) was hydrogenated under 40 psi in an autoclave overnight. The catalyst was removed by filtration and the solvent was evaporated to give the desired product, which was used in the next step without further purification.
後処理
- customThe catalyst was removed by filtration
- customthe solvent was evaporated
出典と根拠
- ORDレコード
- ord-503827e261c94d06bc10ce1c6d339b2e
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09290517B2
反応ノート
読み込み中…