Dimethylformamide → Tert-butyl 4-(2-(1-(3,3-diphenylpropyl)-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)ureido)ethyl)piperidine-1-carboxylate

HRID 936557

反応式

HRID 936557 の反応式
[C:1](=[O:2])([n:3]1[cH:4][cH:5][n:6][cH:7]1)[n:8]1[cH:9][cH:10][n:11][cH:12]1.[CH3:61][N:62]([c:63]1[cH:64][cH:65][n:66][cH:67][cH:68]1)[CH3:69].[Cl:70][CH2:71][Cl:72].[NH2:13][c:14]1[s:15][cH:16][c:17](-[c:19]2[cH:20][cH:21][c:22]([NH:25][S:26](=[O:27])(=[O:28])[CH3:29])[cH:23][cH:24]2)[n:18]1.[O:73]=[CH:74][N:75]([CH3:76])[CH3:77].[c:30]1([CH:36]([CH2:37][CH2:38][NH:39][CH2:40][CH2:41][CH:42]2[CH2:43][CH2:44][N:45]([C:48](=[O:49])[O:50][C:51]([CH3:52])([CH3:53])[CH3:54])[CH2:46][CH2:47]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[C:1](=[O:2])([NH:13][c:14]1[s:15][cH:16][c:17](-[c:19]2[cH:20][cH:21][c:22]([NH:25][S:26](=[O:27])(=[O:28])[CH3:29])[cH:23][cH:24]2)[n:18]1)[N:39]([CH2:38][CH2:37][CH:36]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)[c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1)[CH2:40][CH2:41][CH:42]1[CH2:43][CH2:44][N:45]([C:48](=[O:49])[O:50][C:51]([CH3:52])([CH3:53])[CH3:54])[CH2:46][CH2:47]1

参加物

7

反応物 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 682631,1'-CarbonyldiimidazoleHCID 7063853HCID 7063853、化合物HCID 57586396Tert-butyl 4-(2-(3,3-diphenylpropylamino)ethyl)piperidine-1-carboxylate

生成物 1

HCID 57586428Tert-butyl 4-(2-(1-(3,3-diphenylpropyl)-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)ureido)ethyl)piperidine-1-carboxylate

出典と根拠

ORDレコード
ord-3120d5c3ed1646ff9969eba6714b86c5
出典データセット
Validation data from https://doi.org/10.1039/C8SC04228D

関連ノート

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