Dimethylformamide → 5-(1-methyl-3-trifluoromethyl-1H-pyrazol-5-yl)thiophene-2-carbonyl chloride

反応式

[CH3:1][n:2]1[n:3][c:4]([C:15]([F:16])([F:17])[F:18])[cH:5][c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[s:11]1.[Cl:19][C:20]([C:21]([Cl:22])=[O:23])=[O:24].[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[CH3:1][n:2]1[n:3][c:4]([C:15]([F:16])([F:17])[F:18])[cH:5][c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:12](=[O:13])[Cl:19])[s:11]1

参加物

反応物 3

HCID 6228Dimethylformamide

HCID 65578Oxalyl chloride

HCID 27756685-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2-thiophenecarboxylic acid

生成物 1

HCID 120202255-(1-methyl-3-trifluoromethyl-1H-pyrazol-5-yl)thiophene-2-carbonyl chloride

出典と根拠

ORDレコード: ord-c760a31d4c9f42489a864f202d784cde
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…