Phosphorus oxybromide → 2-Bromo-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine

反応式

[CH3:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:5][c:6](=[O:8])[nH:7]1.[P:19]([Br:20])([Br:21])([Br:22])=[O:23]>>[CH3:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:5][c:6]([Br:21])[n:7]1

参加物

反応物 2

HCID 24613Phosphorus oxybromide

HCID 574686446-Methyl-4-(4-(trifluoromethyl)phenyl)pyridin-2-OL

生成物 1

HCID 574686462-Bromo-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine

出典と根拠

ORDレコード: ord-868225e8ecd94a8495bf34838e5524ca
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…