Tetrahydrofuran → 7-Fluoro-8-(2-fluoro-4-iodophenylamino)-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxylic acid

反応式

[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:26][Si:27]([CH3:28])([CH3:29])[N-:30][Si:31]([CH3:32])([CH3:33])[CH3:34].[Cl:1][c:2]1[c:3]([F:16])[c:4](=[O:15])[n:5]2[c:10]([c:11]1[C:12](=[O:13])[OH:14])[CH2:9][CH2:8][CH2:7][CH2:6]2.[F:17][c:18]1[c:19]([NH2:20])[cH:21][cH:22][c:23]([I:25])[cH:24]1.[Li+:35]>>[c:2]1([NH:20][c:19]2[c:18]([F:17])[cH:24][c:23]([I:25])[cH:22][cH:21]2)[c:3]([F:16])[c:4](=[O:15])[n:5]2[c:10]([c:11]1[C:12](=[O:13])[OH:14])[CH2:9][CH2:8][CH2:7][CH2:6]2