Picolinic acid → N-[5-[2-(3-fluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-2-carboxamide
反応式
[CH3:65][CH2:66][O:67][C:68]([CH3:69])=[O:70].[CH:56]([N:57]([CH2:58][CH3:59])[CH:60]([CH3:61])[CH3:62])([CH3:63])[CH3:64].[F:1][c:2]1[cH:3][c:4]([CH:8]2[N:9]([c:13]3[n:14][c:15]4[n:16]([cH:17][cH:18]3)[n:19][cH:20][c:21]4[NH2:22])[CH2:10][CH2:11][CH2:12]2)[cH:5][cH:6][cH:7]1.[O:71]=[CH:72][N:73]([CH3:74])[CH3:75].[OH:23][C:24](=[O:25])[c:26]1[cH:27][cH:28][cH:29][cH:30][n:31]1.[P-:32]([F:33])([F:34])([F:35])([F:36])([F:37])[F:38].[n:39]1([O:40][C:41]([N:42]([CH3:43])[CH3:44])=[N+:45]([CH3:46])[CH3:47])[c:48]2[n:49][cH:50][cH:51][cH:52][c:53]2[n:54][n:55]1>>[F:1][c:2]1[cH:3][c:4]([CH:8]2[N:9]([c:13]3[n:14][c:15]4[n:16]([cH:17][cH:18]3)[n:19][cH:20][c:21]4[NH:22][C:24](=[O:23])[c:26]3[cH:27][cH:28][cH:29][cH:30][n:31]3)[CH2:10][CH2:11][CH2:12]2)[cH:5][cH:6][cH:7]1
