Dimethyl Sulfide → 1-(3-Pyridin-2-yl-imidazo[1,2-b]pyridazin-2-yl)-ethylamine

反応式

[CH2:1]([O:2][C:3](=[O:4])[NH:10][CH:11]([CH3:12])[c:13]1[n:14][c:15]2[n:16]([n:17][cH:18][cH:19][cH:20]2)[c:21]1-[c:22]1[n:23][cH:24][cH:25][cH:26][cH:27]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:28]1.[CH3:29][S:30][CH3:31].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38]>>[NH2:10][CH:11]([CH3:12])[c:13]1[n:14][c:15]2[n:16]([n:17][cH:18][cH:19][cH:20]2)[c:21]1-[c:22]1[n:23][cH:24][cH:25][cH:26][cH:27]1

参加物

反応物 3

HCID 1068Dimethyl Sulfide

HCID 6422Trifluoroacetic acid

HCID 67431406[1-(3-Pyridin-2-yl-imidazo[1,2-b]pyridazin-2-yl)-ethyl]-carbamic acid benzyl ester

生成物 1

HCID 674336131-(3-Pyridin-2-yl-imidazo[1,2-b]pyridazin-2-yl)-ethylamine

出典と根拠

ORDレコード: ord-983f0f97efa3478ca531d65071e33b71
出典データセット: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…