Oxalyl chloride → 2,2-Dimethyl-4-benzyloxycarbonylbutyryl chloride
反応式
[CH3:1][C:2]([CH3:18])([CH2:6][CH2:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])[C:3](O)=[O:4].C(Cl)(=O)C([Cl:22])=O>>[CH3:1][C:2]([CH3:18])([CH2:6][CH2:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])[C:3]([Cl:22])=[O:4]参加物
3
実験手順
A mixture of 3.1 g of 2,2-dimethyl-4-benzyloxycarbonylbutyric acid and 3.3 ml of oxalyl chloride was refuxed for 1 h. After being cooled to room temperature, the solution was concentrated in vacuo and dried overnight The obtained oil was not further purified for the next reaction.
後処理
- concentrationthe solution was concentrated in vacuo
- customdried overnight The obtained oil
- customwas not further purified for the next reaction
出典と根拠
- ORDレコード
- ord-3e46a729568240518792c9616546daaf
- 出典データセット
- uspto-grants-1998_06
- 特許番号
- US05767256
反応ノート
読み込み中…