Oxalyl chloride → 2,2-Dimethyl-4-benzyloxycarbonylbutyryl chloride

HRID 964194

反応式

HRID 964194 の反応式
[CH3:1][C:2]([CH3:18])([CH2:6][CH2:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])[C:3](O)=[O:4].C(Cl)(=O)C([Cl:22])=O>>[CH3:1][C:2]([CH3:18])([CH2:6][CH2:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])[C:3]([Cl:22])=[O:4]

参加物

3

反応物 2

HCID 65578Oxalyl chlorideHCID 190800452,2-Dimethyl-4-benzyloxycarbonylbutyric acid

生成物 1

HCID 190800382,2-Dimethyl-4-benzyloxycarbonylbutyryl chloride

実験手順

A mixture of 3.1 g of 2,2-dimethyl-4-benzyloxycarbonylbutyric acid and 3.3 ml of oxalyl chloride was refuxed for 1 h. After being cooled to room temperature, the solution was concentrated in vacuo and dried overnight The obtained oil was not further purified for the next reaction.

後処理

  1. concentrationthe solution was concentrated in vacuo
  2. customdried overnight The obtained oil
  3. customwas not further purified for the next reaction

出典と根拠

ORDレコード
ord-3e46a729568240518792c9616546daaf
出典データセット
uspto-grants-1998_06
特許番号
US05767256

関連ノート

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