Ribonolactone → D-Ribonic acid (benzyl 2-benzyloxycarbonylamino-2,6-didesoxy-alpha-D-glucopyranosid-6-yl)-amide

HRID 964408

反応式

HRID 964408 の反応式
[NH2:1][CH2:2][C@H:3]1[O:16][C@H:7]([O:8]CC2C=CC=CC=2)[C@H:6]([NH:17][C:18]([O:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:19])[C@@H:5]([OH:28])[C@@H:4]1[OH:29].[CH2:30]([OH:39])[C@H:31]1[O:36][C:34](=[O:35])[C@H:33]([OH:37])[C@@H:32]1[OH:38]>O1CCOCC1>[CH2:21]([C@@:7]1([O:16][C@H:3]([CH2:2][NH:1][C:34]([C@@H:33]([C@@H:32]([C@@H:31]([CH2:30][OH:39])[OH:36])[OH:38])[OH:37])=[O:35])[C@@H:4]([OH:29])[C@H:5]([OH:28])[C@H:6]1[NH:17][C:18]([O:20][CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)=[O:19])[OH:8])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

参加物

4

反応物 2

HCID 111064RibonolactoneHCID 53644733Benzyl 6-amino-2-benzyloxycarbonylamino-2,6-didesoxy-alpha-D-glucopyranoside

生成物 1

HCID 86752800D-Ribonic acid (benzyl 2-benzyloxycarbonylamino-2,6-didesoxy-alpha-D-glucopyranosid-6-yl)-amide

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

Benzyl 6-amino-2-benzyloxycarbonylamino-2,6-didesoxy-α-D-glucopyranoside (see Ex. 9.C.) and D-ribonic acid g-lactone were reacted as described in Ex. 14.A. and gave D-ribonic acid (benzyl 2-benzyloxycarbonylamino-2,6-didesoxy-α-D-gluco-pyranosid-6-yl)-amide, [α]+81.5° (c 0.2; dioxan), MS: m/z 551.4 ([M+H]+).

出典と根拠

ORDレコード
ord-d5b4f10fe2f6464fa205d7e1f8a3eca5
出典データセット
uspto-grants-1998_06
特許番号
US05767268

関連ノート

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