Methyl iodide → 3-(3-(4-Methylpiperidino)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide
反応式
[CH3:1][I:2].[CH3:3][CH:4]1[CH2:9][CH2:8][N:7]([C:10]2[C:14]([C:15]3[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=3)=[N:13][S:12][N:11]=2)[CH2:6][CH2:5]1>CC(C)=O>[I-:2].[CH3:3][CH:4]1[CH2:5][CH2:6][N:7]([C:10]2[C:14]([C:15]3[CH:16]=[N+:17]([CH3:1])[CH:18]=[CH:19][CH:20]=3)=[N:13][S:12][N:11]=2)[CH2:8][CH2:9]1参加物
4
実験手順
A mixture of methyl iodide (0.5 ml, 8 mmol) and 3-(3-(4-methylpiperidino)-1,2,5-thiadiazol-4-yl)pyridine (0.8 g, 3.1 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 1.14 g (92%).
後処理
- customThe title compound precipitated from the solution
- filtrationwas collected by filtration
- customto yield 1.14 g (92%)
出典と根拠
- ORDレコード
- ord-6bd07d761d77411e96a4a302c2f37aa2
- 出典データセット
- uspto-grants-1998_06
- 特許番号
- US05773452
反応ノート
読み込み中…