Diethyl Ether → 2H-Indeno[2,1-d]oxazol-2-one, 3,3a,4,8b-tetrahydro-, cis-
反応式
Cl[C@@H:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][C@H:3]1[NH:11][C:12]([O:14]C(C)(C)C)=[O:13].C(OCC)C>C(Cl)(Cl)Cl>[O:13]1[C@H:2]2[C:10]3[C:5]([CH2:4][C@H:3]2[NH:11][C:12]1=[O:14])=[CH:6][CH:7]=[CH:8][CH:9]=3参加物
4
実験手順
A solution of (±) trans-1-chloro-2-tert-butoxycarbonylaminoindane (10.0 g, 0.037 mol) in chloroform (200 ml) was heated under reflux in an argon atmosphere for 23 h. The mixture was concentrated in vacuo to give a brown solid. Trituration with diethyl ether afforded the title compound as a beige solid (6.0 g, 92%) m.p. 205°-206° C. which was used without further purification.
後処理
- temperatureunder reflux in an argon atmosphere for 23 h
- concentrationThe mixture was concentrated in vacuo
- customto give a brown solid
出典と根拠
- ORDレコード
- ord-5b8611b88a6e4c3d9cd3615833de6fae
- 出典データセット
- uspto-grants-1998_06
- 特許番号
- US05773463
反応ノート
読み込み中…