Methanone, (2-nitrophenyl)phenyl- → 2-Aminobenzophenone
反応式
[N+:1]([C:4]1[CH:17]=[CH:16][CH:15]=[CH:14][C:5]=1[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7])([O-])=O>C1COCC1.CO.O>[NH2:1][C:4]1[CH:17]=[CH:16][CH:15]=[CH:14][C:5]=1[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]参加物
5
反応条件
- 温度
- 70 °C
実験手順
A mixture of nitrobenzophenone resin, 3-Scheme 6, (950 mg), NaSH (1.0 g) in THF (10 mL), MeOH (5 mL), water (5 mL) was heated in an oil bath at 70° C. for 16 h. The mixture was cooled, filtered and washed with methanol, water, methylene chloride and finally with methanol. Drying at 60° (in vacuo gave a slight yellow resin. Recovered (900 mg). IR 1640 (broad).
後処理
- temperatureThe mixture was cooled
- filtrationfiltered
- washwashed with methanol, water, methylene chloride and finally with methanol
- customDrying at 60° (in vacuo
- customgave a slight yellow resin
- customRecovered (900 mg)
出典と根拠
- ORDレコード
- ord-98e42d8282b748fabdb770bcde906419
- 出典データセット
- uspto-grants-1998_06
- 特許番号
- US05773512
反応ノート
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