化工社化工社 化学情報印刷レポート · 研究参考用
Purine → 4-Amino-2-methyl-5-pyrimidinemethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Purine | HCID 1044 | — |
| 反応物 | Thiamine | HCID 1130 | — |
| 反応物 | 5-Aminoimidazole ribonucleotide | HCID 161500 | — |
| 反応物 | 5'-Phosphoribosylformylglycinamidine | HCID 5462266 | — |
| 生成物 | 4-Amino-2-methyl-5-pyrimidinemethanol | HCID 777 | — |
反応手順
The following reactions comprise the biosynthesis of thiamine: Thiamine biosynthesis begins with purine metabolism. From here AIR synthetase, the fifth step in the pathway catalyzes the conversion of 5′-phosphoribosyl-N-formylglycinamidine (FGAM) to 5′-phosphoribosyl-5-aminoimidazole (AIR). 4-Amino-5-hydroxymethyl-2-methylpyrimidine is then formed in a series of reactions.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06955890B2 |
| 出典データセット | uspto-grants-2005_10 |
| ORD ID | ord-6c6a8c3dc58c44afa8c1cde254ee8d91 |
| 出典メモ | uspto-grants-2005_10 |