HRID967694

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1044

Purine

C5H4N4

HCID1130

Thiamine ion

C12H17N4OS+

2 次

结构：Nc1cncn1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

HCID161500

1H-Imidazol-5-amine, 1-(5-O-phosphono-beta-D-ribofuranosyl)

C8H14N3O7P

$结构：N/C(CNC=O)=N\[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O$

HCID5462266

未命名化合物

PRODUCTS

生成物

HCID777

Toxopyrimidine

C6H9N3O

PROCEDURE

实验过程

The following reactions comprise the biosynthesis of thiamine: Thiamine biosynthesis begins with purine metabolism. From here AIR synthetase, the fifth step in the pathway catalyzes the conversion of 5′-phosphoribosyl-N-formylglycinamidine (FGAM) to 5′-phosphoribosyl-5-aminoimidazole (AIR). 4-Amino-5-hydroxymethyl-2-methylpyrimidine is then formed in a series of reactions.