p-Toluenesulfonic acid → HCID 86759869、化合物
反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][C:12](=[O:35])[O:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([N:22]3[CH:26]=[C:25]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)[N:24]=[C:23]3[CH2:33][CH3:34])=[CH:18][CH:17]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[C:36]1([CH3:46])[CH:41]=[CH:40][C:39]([S:42]([OH:45])(=[O:44])=[O:43])=[CH:38][CH:37]=1>CC(C)=O>[C:36]1([CH3:46])[CH:37]=[CH:38][C:39]([S:42]([OH:45])(=[O:43])=[O:44])=[CH:40][CH:41]=1.[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][C:12](=[O:35])[O:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([N:22]3[CH:26]=[C:25]([C:27]4[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=4)[N:24]=[C:23]3[CH2:33][CH3:34])=[CH:18][CH:17]=2)(=[O:9])=[O:10])=[CH:4][CH:3]=1参加物
4
実験手順
A mixture of 2-[4-(2-ethyl-4-phenyl-1H-imidazole-1-yl)phenyl]ethyl (4-methylphenyl)sulfonylcarbamate (157 mg, 0.320 mmol), p-toluenesulfonic acid (61 mg, 0.320 mmol) in acetone (2 ml) was stirred at room temperature for 1 h. The reaction mixture was evaporated to afford the title compound as white solids: MS (ESI) m/z 490 [M+H]+, 488 [M−H]−.
後処理
- customThe reaction mixture was evaporated