2-Methylimidazole → 2-(2-Methyl-1H-imidazol-1-yl)ethan-1-amine

HRID 969805

反応式

HRID 969805 の反応式
[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.Cl.Cl[CH2:9][CH2:10][NH2:11]>>[CH3:1][C:2]1[N:3]([CH2:9][CH2:10][NH2:11])[CH:4]=[CH:5][N:6]=1

参加物

3

反応物 2

HCID 127492-MethylimidazoleHCID 97937372-Chloroethylamine hydrochloride

生成物 1

HCID 31574802-(2-Methyl-1H-imidazol-1-yl)ethan-1-amine収率 47%

実験手順

2-(2-Methylimidazol-1-yl)ethylamine was prepared from 2-methylimidazole and 2-chloroethylamine hydrochloride using the method described in Step B of Example 1. This material was obtained as a light yellow oil in 47% yield. 1H NMR (300 MHz, CD3OD) δ 6.95 (br s, 1H), 6.82 (br s, 1H), 4.90 (bs, 2H), 3.90 (t, J=6.9 Hz, 2H), 2.93 (t, J=6.9 Hz, 2H), 2.35 (s, 3H); MS (APCI) m/z 126 [M+H]+.

後処理

  1. customThis material was obtained as a light yellow oil in 47% yield

出典と根拠

ORDレコード
ord-6b9488b66cbe4438850a1055f7b1eecf
出典データセット
uspto-grants-2007_12
特許番号
US07307094B2

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