Methanol → Dimethyl 2-formylcyclopropane-1,1-dicarboxylate

HRID 971925

反応式

HRID 971925 の反応式
[CH:1]([CH:3]1[CH2:5][C:4]1([C:11]([O:13][CH2:14]C)=[O:12])[C:6]([O:8][CH2:9]C)=[O:7])=[O:2].C(C=C)=O.COC(=O)C(Br)C(OC)=O.CO>C(O)C>[CH:1]([CH:3]1[CH2:5][C:4]1([C:6]([O:8][CH3:9])=[O:7])[C:11]([O:13][CH3:14])=[O:12])=[O:2]

参加物

6

反応物 4

HCID 887MethanolHCID 7847AcroleinHCID 70087Dimethyl bromomalonateHCID 5337391,1-Diethyl 2-formylcyclopropane-1,1-dicarboxylate

生成物 1

HCID 10899359Dimethyl 2-formylcyclopropane-1,1-dicarboxylate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

By following the procedure of D. T. Warner, cited above, used for preparing diethyl 2-formylcyclopropane-1,1-dicarboxylate from acrolein but using equivalent amount of dimethylbromomalonate and methanol instead of diethylbromomalonate and ethanol, respectively, the title compound, nmr (CDCl3) δ 1.98 (m,2H), 2.80 (m,1H), 3.79 (s,6H), 8.82 (d, J=4 cps, 1H), is obtained.

出典と根拠

ORDレコード
ord-8da759ba1a644180a25dba7ea81a46ac
出典データセット
uspto-grants-1979_07
特許番号
US04161608

関連ノート

読み込み中…