Formaldehyde → HCID 21311690、化合物

HRID 971986ノート

反応式

HRID 971986 の反応式
[CH3:1][NH:2][CH:3]([CH3:10])[CH2:4][C:5]1[O:6][CH:7]=[CH:8][CH:9]=1.[CH2:11]=O.C#C.O1[CH2:20][CH2:19]OCC1>>[CH3:1][N:2]([C:11]#[C:19][CH3:20])[CH:3]([CH3:10])[CH2:4][C:5]1[O:6][CH:7]=[CH:8][CH:9]=1

参加物

5

反応物 4

HCID 712FormaldehydeHCID 6326AcetyleneHCID 312751,4-DioxaneHCID 21311689N-methyl-N-[1-methyl-2-(2-furyl)-ethyl] amine

生成物 1

HCID 21311690HCID 21311690、化合物

実験手順

13.9 g. (0.1 mole) of N-methyl-N-[1-methyl-2-(2-furyl)-ethyl] amine are dissolved in 80 ml. of dioxane, whereupon 6 g. of paraformaldehyde and 1 g. of cuprous chloride are added and gaseous acetylene is introduced into the solution at 80° C. under stirring for 30 hours. The reaction mixture is filtered and the filtrate is evaporated. The residue is dissolved in benzene, the benzene solution is washed with water, dried over potassium carbonate and evaporated. The residue is distilled off in vacuo. Thus 6.8 g. of N-methyl-N-[1-methyl-2-(2-furyl)-ethyl]-propynyl amine are obtained. Bp.: 114°-116° C./20 Hgmm; nD20 =1.4910.

後処理

  1. filtrationThe reaction mixture is filtered
  2. customthe filtrate is evaporated
  3. dissolutionThe residue is dissolved in benzene
  4. washthe benzene solution is washed with water
  5. dry with materialdried over potassium carbonate
  6. customevaporated
  7. distillationThe residue is distilled off in vacuo

出典と根拠

ORDレコード
ord-3164a52c7b504f4e839d1d250a0ea0c4
出典データセット
uspto-grants-1979_07
特許番号
US04162327

反応ノート

読み込み中…