Ethanol → 4-Hydrazinyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidine
反応式
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]2[NH:8][N:9]=[CH:10][C:3]=12.O.[NH2:12][NH2:13].[CH2:14](O)C>>[NH:12]([C:2]1[N:7]=[CH:6][N:5]=[C:4]2[N:8]([CH3:14])[N:9]=[CH:10][C:3]=12)[NH2:13]参加物
4
実験手順
50 g. of 4-chloropyrazolo[3,4-d]pyrimidine are dissolved in 700 ml. of absoulute ethanol and 25 g. of hydrazine hydrate in 100 ml. of ethanol are slowly added dropwise with stirring. This is stirred for 13 hours at room temperature and the product formed is then filtered under suction, water is added and the product, 4-hydrazino-1-methylpyrazolo[3,4-d]pyrimidine, is crystallized from dimethylformamide as yellowish crystals, m.p. 231°.
後処理
- stirringThis is stirred for 13 hours at room temperature
- customthe product formed
- filtrationis then filtered under suction, water
- additionis added
- customthe product, 4-hydrazino-1-methylpyrazolo[3,4-d]pyrimidine, is crystallized from dimethylformamide as yellowish crystals, m.p. 231°
出典と根拠
- ORDレコード
- ord-2da7edcef5024c9eaa39f1a89d35c165
- 出典データセット
- uspto-grants-1977_10
- 特許番号
- US04053474
反応ノート
読み込み中…