Sulfuric Acid → 1-Chloro-3-nitrobenzene
反応式
[Cl:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1N.C(O)(C)C.S(=O)(=O)(O)O.N([O-])=O.[Na+]>O>[Cl:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][CH:3]=1参加物
6
実験手順
172.5 parts of 2-chloro-4-nitro-aniline are introduced into 180 parts of isopropanol and 300 parts of water, and 200 parts of concentrated sulfuric acid (98 percent strength by weight) are then added to the mixture. A solution of 125 parts of NaNO2 in 175 parts of water is run in at 50° C., as described in Example 1. The mixture is cooled, 400 parts of water are added and the product is filtered off. 142 parts (90% of theory) of 3-chloro-nitro-benzene, of melting point 40°-42° C., are obtained.
後処理
- additionare then added to the mixture
- customis run in at 50° C.
- temperatureThe mixture is cooled
- filtrationthe product is filtered off
出典と根拠
- ORDレコード
- ord-bb2327d0a7014402a0420096593a1132
- 出典データセット
- uspto-grants-1977_10
- 特許番号
- US04053527
反応ノート
読み込み中…