Hydroxylamine → 1-(2-thienylmethyl)piperidin-4-amine(SALTDATA: 2HCl)
反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][N:7]1[CH2:12][CH2:11][C:10](=O)[CH2:9][CH2:8]1.[NH2:14]O.[Al]>[OH-].[Na+].[Ni]>[NH2:14][CH:10]1[CH2:11][CH2:12][N:7]([CH2:6][C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)[CH2:8][CH2:9]1参加物
6
実験手順
N-(2-Thienylmethyl)-4-piperidone is reacted with hydroxylamine, followed by nickel, aluminium alloy in 30% sodium hydroxide solution, in a similar manner to that described in Example 19 to give 4-amino-N-(2-thienylmethyl)piperidine.
出典と根拠
- ORDレコード
- ord-9faeccc2585945bda1439939a089684e
- 出典データセット
- uspto-grants-1977_10
- 特許番号
- US04053615
反応ノート
読み込み中…