Acetic Anhydride → HCID 20263934、化合物
反応式
[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][OH:9])[C:5]([CH2:10][OH:11])=[CH:4][N:3]=1.[C:12](OC(=O)C)(=[O:14])[CH3:13]>N1C=CC=CC=1>[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][O:9][C:12](=[O:14])[CH3:13])[C:5]([CH2:10][OH:11])=[CH:4][N:3]=1参加物
4
実験手順
2-Methyl-4,5-di(hydroxymethyl)pyridine (0.1 mole) is stirred in pyridine (50 ml.) with acetic anhydride (0.1 mole) at room temperature overnight. The pyridine is evaporated and the residue is dissolved is 10 ml. water and extracted with 2 × 30 ml. of chloroform. After drying over magnesium sulfate, the chloroform is evaporated and the residue is chromatographed on a silica gel column using benzene-ethanol as eluate. By this procedure is obtained:
後処理
- customThe pyridine is evaporated
- dissolutionthe residue is dissolved
- extractionwater and extracted with 2 × 30 ml
- dry with materialAfter drying over magnesium sulfate
- customthe chloroform is evaporated
- customthe residue is chromatographed on a silica gel column
- customBy this procedure is obtained
出典と根拠
- ORDレコード
- ord-34c6489999194555837c8ac770fd53ef
- 出典データセット
- uspto-grants-1977_10
- 特許番号
- US04053606
反応ノート
読み込み中…