3-Aminopropyl(but-3-enyl)phosphinic acid → (3-Aminopropyl)(n-butyl)phosphinic acid
反応式
[NH2:1][CH2:2][CH2:3][CH2:4][P:5]([CH2:8][CH2:9][CH:10]=[CH2:11])(=[O:7])[OH:6].[H][H]>O.[Pd]>[NH2:1][CH2:2][CH2:3][CH2:4][P:5]([CH2:8][CH2:9][CH2:10][CH3:11])(=[O:6])[OH:7]参加物
5
実験手順
A solution of 1 g of 3-aminopropyl(but-3-enyl)phosphinic acid in 25 ml of water is treated with 0.1 g of 5% palladium on charcoal and hydrogenated at room temperature until hydrogen uptake ceases. The catalyst is removed by filtration of the reaction mixture through celite and the filtrate evaporated to dryness, to afford 3-aminopropyl(butyl)-phosphinic acid, m.p. 231°-234° (dec.) 31 -NMR (D2O): δ±44.6 ppm.
後処理
- customThe catalyst is removed by filtration of the reaction mixture through celite
- customthe filtrate evaporated to dryness
出典と根拠
- ORDレコード
- ord-1e2c3f361ed840cc92bd575aec65e39c
- 出典データセット
- uspto-grants-1991_11
- 特許番号
- US05064819
反応ノート
読み込み中…