Sodium Iodide → Iodomethyl octyl carbonate

HRID 974767ノート

反応式

HRID 974767 の反応式
[C:1](=[O:14])([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[O:2][CH2:3]Cl.[I-:15].[Na+]>CC(C)=O>[C:1](=[O:14])([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[O:2][CH2:3][I:15]

参加物

4

反応物 2

HCID 5238Sodium IodideHCID 19969190Chloromethyl octyl carbonate

生成物 1

HCID 19969200Iodomethyl octyl carbonate収率 72.6%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a solution of chloromethyl octyl carbonate (1.14 g, 0.005 mol) in acetone (10 ml) was added sodium iodide (2.3 g, 0.015 mol). The mixture was stirred for 3 hours, concentrated invacuo, and dissolved in dichloromethane (50 ml). This solution was washed with saturated aqueous sodium chloride, aqueous sodium thiosulfate, and saturated aqueous sodium chloride, dried (sodium sulfate) and concentrated invacuo to yield iodomethyl octyl carbonate (1.14 g).

後処理

  1. concentrationconcentrated invacuo
  2. dissolutiondissolved in dichloromethane (50 ml)
  3. washThis solution was washed with saturated aqueous sodium chloride, aqueous sodium thiosulfate, and saturated aqueous sodium chloride
  4. dry with materialdried (sodium sulfate)
  5. concentrationconcentrated invacuo

出典と根拠

ORDレコード
ord-e50a6d5bfbaf43b69f4c60a775680c32
出典データセット
uspto-grants-1997_03
特許番号
US05607691

反応ノート

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