Hydrogen Bromide → HCID 19970307、化合物
反応式
[CH2:1]([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]([NH:17]C(C)(C)C)=[S:16])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BrH:22].C(OCC)C>C(O)(=O)C>[BrH:22].[CH2:1]([N:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([NH2:17])=[S:16])[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
5
実験手順
17 g of N-(1-benzylpiperid-4-yl)-N'-tert-butylthiourea are added to 170 ml of 33% hydrobromic acid in acetic acid; the reaction mixture is stirred at room temperature for 4 hours, then it is poured over diethylether. The crystals obtained are filtered and they are thoroughly washed with diethylether in order to obtain white crystals which melt at 120° C.; yield: quantitative.
後処理
- customThe crystals obtained
- filtrationare filtered
- washthey are thoroughly washed with diethylether in order
- customto obtain white crystals which
- custommelt at 120° C.
出典と根拠
- ORDレコード
- ord-fb3d83763f6a4bdfacfaaf656bc33681
- 出典データセット
- uspto-grants-1997_03
- 特許番号
- US05607952
反応ノート
読み込み中…