Methanol → 3-Methoxy-3-oxo-2-phenylpropanoic acid

HRID 976054

反応式

HRID 976054 の反応式
[C:1]1([CH:7]([C:11]([OH:13])=[O:12])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.B(F)(F)F.[CH3:18]COCC.CO>>[C:1]1([CH:7]([C:11]([OH:13])=[O:12])[C:8]([O:10][CH3:18])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 887MethanolHCID 8000Boron trifluoride etherateHCID 75791Phenylmalonic acid

生成物 1

HCID 28177753-Methoxy-3-oxo-2-phenylpropanoic acid

実験手順

A mixture of phenylmalonic acid (3.6 g, 0.02 mol), boron trifluoride etherate (2.4 mL, 0.02 mol) and 0.8 mL of anhydrous methanol (0.02 mol) was refluxed and stirred for 24 hours. After cooling to room temperature, the reaction mixture was filtered and 20 mL of water was added.

後処理

  1. temperaturewas refluxed
  2. filtrationthe reaction mixture was filtered
  3. addition20 mL of water was added

出典と根拠

ORDレコード
ord-9ce6dd16fcca45f9ab3aea345993b2d6
出典データセット
uspto-grants-1997_03
特許番号
US05610188

関連ノート

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