Methylglyoxal → 4-Amino-7-methylpteridin-2(3H)-one
反応式
Cl.[NH2:2][C:3]1[C:8]([NH2:9])=[C:7]([NH2:10])[NH:6][C:5](=[O:11])[N:4]=1.[CH3:12][C:13]([CH:15]=O)=O>O>[NH2:2][C:3]1[C:8]2[C:7](=[N:10][C:13]([CH3:15])=[CH:12][N:9]=2)[NH:6][C:5](=[O:11])[N:4]=1参加物
4
実験手順
In 50 mL of H2O is dissolved 1.77 g (0.01 mole) of 4,5,6-triaminopyrimidine-2-one hydrochloride (19). The pH of the solution is adjusted to 5 and then, 4 mL of 40% aqueous methylglyoxal (FLUKA, A G, Switzerland) is added and the solution is heated under reflux for 30 minutes. The resulting precipitate is collected and purified by recrystallization from a large amount of H2O to give 20.
後処理
- temperaturethe solution is heated
- temperatureunder reflux for 30 minutes
- customThe resulting precipitate is collected
- custompurified by recrystallization from a large amount of H2O
出典と根拠
- ORDレコード
- ord-43d1f3f6fb2f48bb81502b9fe40bb15f
- 出典データセット
- uspto-grants-1997_03
- 特許番号
- US05612468
反応ノート
読み込み中…