Methyl iodide → HCID 178504040、化合物

HRID 978412ノート

反応式

HRID 978412 の反応式
[F:1][C:2]([F:9])([F:8])[CH2:3][NH:4][C:5]([NH2:7])=[S:6].[CH3:10][I:11]>CCO>[IH:11].[F:1][C:2]([F:9])([F:8])[CH2:3][NH:4][C:5](=[NH:7])[S:6][CH3:10]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 202028121-(2,2,2-Trifluoroethyl)thiourea

生成物 1

HCID 178504040HCID 178504040、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 2,2,2-trifluoroethylthiourea (8.0 g.) and methyl iodide (3.5 g.) in EtOH (40 ml.) was heated under reflux for 70 minutes, then evaporated to dryness in vacuo. The residue was triturated with ether to give 2,2,2-trifluoroethyl-S-methylisothiourea hydroiodide, m.p. 154°-156° (90%).

後処理

  1. temperatureunder reflux for 70 minutes
  2. customevaporated to dryness in vacuo
  3. customThe residue was triturated with ether

出典と根拠

ORDレコード
ord-4960a60ca38242b3bae6f6cece2e2d00
出典データセット
uspto-grants-1987_05
特許番号
US04665073

反応ノート

読み込み中…