Benzaldehyde → 5,10,15,20-Tetraphenyl-21,22-dihydroporphyrin

HRID 978488

反応式

HRID 978488 の反応式
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:9]1[CH:13]=[CH:12][CH:11]=[CH:10]1>C(O)(=O)CC>[CH:5]1[CH:6]=[CH:7][C:2]([C:1]2[C:13]3=[N:9][C:10]([CH:11]=[CH:12]3)=[C:1]([C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[C:10]3=[N:9][C:13]([CH:12]=[CH:11]3)=[C:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:10]3[NH:9][C:13](=[CH:12][CH:11]=3)[C:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[C:10]3[NH:9][C:13]=2[CH:12]=[CH:11]3)=[CH:3][CH:4]=1

参加物

4

反応物 2

HCID 240BenzaldehydeHCID 8027Pyrrole

生成物 1

HCID 701865,10,15,20-Tetraphenyl-21,22-dihydroporphyrin収率 20%

試薬・触媒・溶媒 1

HCID 1032Propionic Acid溶媒

実験手順

In a 4-liter flask equipped with a cooling tube, 80 ml (84.8 g) of benzaldehyde, 56 ml (53.6 g) of pyrrole, and 3 liters of propionic acid were placed and reacted for 30 minutes under reflux. Then, the flask was allowed to stand for one day. After filtering the reaction mixture, recrystallization from a mixed solvent of methanol and chloroform (1:1 by weight) was carried out for purification. Thus, α,β,γ,δ-tetraphenylporphine was obtained in 20% yield.

後処理

  1. customIn a 4-liter flask equipped with a cooling tube
  2. customreacted for 30 minutes
  3. temperatureunder reflux
  4. filtrationAfter filtering
  5. customthe reaction mixture, recrystallization from a mixed solvent of methanol and chloroform (1:1 by weight)
  6. customwas carried out for purification

出典と根拠

ORDレコード
ord-ba2e9bfdd4524718a1bedc4cc706fae6
出典データセット
uspto-grants-1987_05
特許番号
US04665134

関連ノート

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