Diethyl Ether → HCID 13827301、化合物
反応式
CN(C)CCCN[C:7]([C:9]1[CH:14]=[CH:13][C:12](/[CH:15]=[CH:16]/[C:17]2[CH:18]=[C:19]3[C:24](=[CH:25][CH:26]=2)[C:23](=[O:27])[NH:22][N:21]=[CH:20]3)=[CH:11][CH:10]=1)=[O:8].[CH3:29][N:30]([CH3:35])[CH2:31][CH2:32][CH2:33][OH:34].CCOCC>C1COCC1>[CH3:29][N:30]([CH3:35])[CH2:31][CH2:32][CH2:33][O:34][C:7]([C:9]1[CH:10]=[CH:11][C:12](/[CH:15]=[CH:16]/[C:17]2[CH:18]=[C:19]3[C:24](=[CH:25][CH:26]=2)[C:23](=[O:27])[NH:22][N:21]=[CH:20]3)=[CH:13][CH:14]=1)=[O:8]参加物
5
実験手順
The acid chloride (25 g) of Example 29 above was dissolved in THF (1250 ml) and 3-dimethylaminopropanol (250 ml) was added dropwise. After stirring overnight at room temperature ether (2 l) was added and the resulting precipitate was filtered. The crude ester (13.6 g) was purified via the hydrochloride salt, mp 288° C.