Tert-Butylamine → Tertiarybutylaminoethoxyethanol
反応式
[C:1]([NH2:5])([CH3:4])([CH3:3])[CH3:2].Cl[CH2:7][CH2:8][O:9][CH:10]([OH:12])[CH3:11].[OH-].[Na+]>CO>[C:1]([NH:5][CH2:7][CH2:8][O:9][CH:10]([OH:12])[CH3:11])([CH3:4])([CH3:3])[CH3:2]参加物
5
反応条件
- 温度
- 150 °C
実験手順
A solution of 45.63 g (0.625 mole) of tertiary-butylamine and 31 g (0.25 mole) of 2-chloroethoxyethanol in 100 ml of methanol was charged to a 300 ml steel autoclave and heated under autogenous pressure for 1 hour at 150° C. The reactor was cooled and the contents removed. To the homogeneous solution was added 11 g (0.275 mole) of NaOH pellets and the reaction refluxed for 0.5-1 hour, cooled, filtered, vacuum stripped, and distilled. The yield was 31.4 g (78%).
後処理
- temperatureThe reactor was cooled
- customthe contents removed
- temperaturethe reaction refluxed for 0.5-1 hour
- temperaturecooled
- filtrationfiltered
- distillationdistilled
出典と根拠
- ORDレコード
- ord-1903b4917735466a96b4ea299056fd61
- 出典データセット
- uspto-grants-1987_05
- 特許番号
- US04665234
反応ノート
読み込み中…