関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Dichloromaleic anhydride | HCID 70728 | — |
| 反応物 | 3-(4-Chlorophenyl)propan-1-amine | HCID 6485772 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | HCID 178525580 | HCID 178525580 | 82% |
反応手順
16.7 g (0.1 mol) of dichloromaleic anhydride and 17.0 g (0.1 mol) of 3-(4-chlorophenyl)-propylamine are stirred in 100 ml of glacial acetic acid under reflux for 4 hours. 50 ml of water are added and the mixture is cooled to 20° C. The product is filtered off with suction and dried. 26.1 g (82% of theory) of dichloromaleic acid N-[3-(4-chlorophenyl)-propyl]-imide of melting point 72°-73° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04666935 |
|---|
| 出典データセット | uspto-grants-1987_05 |
|---|
| ORD ID | ord-0f3efac96b3d445791bbd1d9a2893ed7 |
|---|
| 出典メモ | uspto-grants-1987_05 |
|---|
