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HRID979227

反应详情

EQUATION

反应方程式

HRID 979227 的结构方程式

REACTANTS

反应物

3
结构：O
HCID962

Water

H2O

结构：O=C1OC(=O)C(Cl)=C1Cl
HCID70728

Dichloromaleic anhydride

C4Cl2O3

结构：NCCCc1ccc(Cl)cc1
HCID6485772

3-(4-chlorophenyl)propan-1-amine

C9H12ClN

PRODUCTS

生成物

1
结构：O=C(O)/C(Cl)=C(/Cl)C(O)=NCCCc1ccc(Cl)cc1
HCID178525580

未命名化合物

收率 82%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

CONDITIONS

反应条件

温度
20 °C

PROCEDURE

实验过程

16.7 g (0.1 mol) of dichloromaleic anhydride and 17.0 g (0.1 mol) of 3-(4-chlorophenyl)-propylamine are stirred in 100 ml of glacial acetic acid under reflux for 4 hours. 50 ml of water are added and the mixture is cooled to 20° C. The product is filtered off with suction and dried. 26.1 g (82% of theory) of dichloromaleic acid N-[3-(4-chlorophenyl)-propyl]-imide of melting point 72°-73° C. are obtained.

WORKUP

后处理

  1. temperatureunder reflux for 4 hours
  2. filtrationThe product is filtered off with suction
  3. customdried