HCID 53648267、化合物 → HCID 20201859、化合物
反応式
[CH2:1]([O:3][C:4](=[O:18])[CH:5]([CH2:8][C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-])=O)=[CH:11][CH:10]=1)[CH2:6][CH3:7])[CH3:2].[H][H]>C(OCC)(=O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:18])[CH:5]([CH2:8][C:9]1[CH:10]=[CH:11][C:12]([NH2:15])=[CH:13][CH:14]=1)[CH2:6][CH3:7])[CH3:2]参加物
5
実験手順
28 g of 2-(p-nitrobenzyl)-butyric acid ethyl ester are dissolved in 200 ml ethyl acetate. The solution is added with 1 g of 10% Pd/C and hydrogenated in a Parr apparatus until complete absorption of hydrogen. After filtering and evaporation from solvent about 25 g of product are obtained as a sufficiently pure oil for the successive reactions.
後処理
- filtrationAfter filtering
- customevaporation from solvent about 25 g of product
- customare obtained as a sufficiently pure oil for the successive reactions
出典と根拠
- ORDレコード
- ord-f6262d0943234b41b0c183d473b12382
- 出典データセット
- uspto-grants-1987_05
- 特許番号
- US04666936
反応ノート
読み込み中…