Dibutyltin oxide → Dibutyltin diethylmalonate

HRID 979273

反応式

HRID 979273 の反応式
[CH2:1]([Sn:5](=O)[CH2:6][CH2:7][CH2:8][CH3:9])[CH2:2][CH2:3][CH3:4].[CH2:11]([C:13]([CH2:20][CH3:21])([C:17]([OH:19])=[O:18])[C:14]([OH:16])=[O:15])[CH3:12]>C1(C)C=CC=CC=1>[CH2:20]([C:13]([CH2:11][CH3:12])([C:17]([O-:19])=[O:18])[C:14]([O-:16])=[O:15])[CH3:21].[CH2:1]([Sn+2:5][CH2:6][CH2:7][CH2:8][CH3:9])[CH2:2][CH2:3][CH3:4]

参加物

4

反応物 2

HCID 61221Dibutyltin oxideHCID 68185Malonic acid, diethyl-

生成物 1

HCID 86741532Dibutyltin diethylmalonate収率 98%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

A mixture of 300 grams of dibutyltin oxide, 193 grams of diethylmalonic acid, and 500 ml. of toluene was refluxed for 1 hour. There was collected 21 grams of water in a Dean Stock trap by azeotropic distillation. The reaction mixture was then filtered while hot and allowed to cool to ambient temperatures. Removal of the solvent in vacuo provided 460 grams (98% yield) of dibutyltin diethylmalonate as a white crystalline solid. The identity of the product was confirmed by NMR, IR and FD-MS analysis.

後処理

  1. customThere was collected 21 grams of water in a Dean Stock trap
  2. distillationby azeotropic distillation
  3. filtrationThe reaction mixture was then filtered while hot and
  4. temperatureto cool to ambient temperatures
  5. customRemoval of the solvent in vacuo

出典と根拠

ORDレコード
ord-513107a2e36c4ceaa0523aa8baa07306
出典データセット
uspto-grants-1987_05
特許番号
US04667007

関連ノート

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