Allyl bromide → HCID 20223008、化合物
反応式
[F:1][C:2]1[C:3]([O:9][CH3:10])=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:17](Br)[CH:18]=[CH2:19]>CC(C)=O>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH2:19][CH:18]=[CH2:17])[C:3]=1[O:9][CH3:10]参加物
5
実験手順
A mixture of 3-fluoro-2-methoxyphenol (19.5 g; 0.137 m) potassium carbonate (85 g), allyl bromide (15 ml) and acetone (100 ml) was refluxed for 4 hours. The reaction was cooled to room temperature and evaporated to dryness. The residue was partitioned between water and dichloromethane. The organic layer was separated, dried and evaporated affording 19.0 g of the desired product as an oil.
後処理
- temperaturewas refluxed for 4 hours
- customevaporated to dryness
- customThe residue was partitioned between water and dichloromethane
- customThe organic layer was separated
- customdried
- customevaporated
出典と根拠
- ORDレコード
- ord-80395b594811469eac11e42b8be3971a
- 出典データセット
- uspto-grants-1987_01
- 特許番号
- US04634705
反応ノート
読み込み中…