Ethyl 2,3-dimethoxy-6-nitrobenzoate → Ethyl 2,3-dimethoxy-6-aminobenzoate

HRID 979972ノート

反応式

HRID 979972 の反応式
[CH3:1][O:2][C:3]1[C:13]([O:14][CH3:15])=[CH:12][CH:11]=[C:10]([N+:16]([O-])=O)[C:4]=1[C:5]([O:7][CH2:8][CH3:9])=[O:6].[H][H]>C(O)C.[Pd]>[NH2:16][C:10]1[C:4]([C:5]([O:7][CH2:8][CH3:9])=[O:6])=[C:3]([O:2][CH3:1])[C:13]([O:14][CH3:15])=[CH:12][CH:11]=1

参加物

5

反応物 2

HCID 13749913Ethyl 2,3-dimethoxy-6-nitrobenzoateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 13749914Ethyl 2,3-dimethoxy-6-aminobenzoate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

Ethyl 2,3-dimethoxy-6-nitrobenzoate (200 g, 0.979 mole) was dissolved in ethanol (2 L) containing 5% palladium on carbon and hydrogenated until the theoretical amount of hydrogen was absorbed. Filtration and removal of the solvent in vacuo provided the product as a yellow oil, 220.6 g (98.0%).

後処理

  1. customwas absorbed
  2. filtrationFiltration and removal of the solvent in vacuo

出典と根拠

ORDレコード
ord-75ad21e1600f466aa715f7f6d9524b2b
出典データセット
uspto-grants-1987_01
特許番号
US04634769

反応ノート

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