Thionyl Chloride → HCID 178444488、化合物

HRID 980424ノート

反応式

HRID 980424 の反応式
[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH2:12][C:13]([OH:15])=O)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].S(Cl)([Cl:18])=O>>[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH2:12][C:13]([Cl:18])=[O:15])[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 178444491HCID 178444491、化合物

生成物 1

HCID 178444488HCID 178444488、化合物

実験手順

For conversion into the acid chloride, trans-4-pentylcyclohexylacetic acid (12.0 g, 0.0566 mol) was reacted for about 1 hour on an oil bath at 80° C. with thionyl chloride (50 ml). The solution obtained was evaporated under reduced pressure, treated with absolute toluene (50 ml) and once more evaporated under reduced pressure.

後処理

  1. customThe solution obtained
  2. customwas evaporated under reduced pressure
  3. additiontreated with absolute toluene (50 ml)
  4. customonce more evaporated under reduced pressure

出典と根拠

ORDレコード
ord-f5c682759cb14903a7140f0f7b826a0a
出典データセット
uspto-grants-1987_01
特許番号
US04637897

反応ノート

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