Acetic Acid → HCID 20071538、化合物

HRID 981047ノート

反応式

HRID 981047 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.[N:11]([C:13]1[CH:20]=[C:19]([CH3:21])[CH:18]=[CH:17][C:14]=1[NH:15]C)=O.C(O)(=O)C.Br>O>[CH3:21][C:19]1[CH:20]=[C:13]2[C:14](=[CH:17][CH:18]=1)[N:15]=[C:6]1[NH:7][C:8]3[CH:9]=[CH:10][C:2]([Cl:1])=[CH:3][C:4]=3[C:5]1=[N:11]2

参加物

6

反応物 4

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 871105-ChloroindoleHCID 20071541HCID 20071541、化合物

生成物 1

HCID 20071538HCID 20071538、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of 1.68 g 5-chloroindol (0.01 mole) and 1.50 g 2-nitroso-N-methyl-p-toluidine (0.01 mole), 10 ml acetic acid is boiled under reflux for 1 hour. Finally hydrogen bromide is introduced and the mixture is boiled for further 2 hours. After cooling it is poured into water. The dried reaction product is recrystallized from acetic acid.

後処理

  1. temperatureunder reflux for 1 hour
  2. temperatureAfter cooling it
  3. customThe dried reaction product
  4. customis recrystallized from acetic acid

出典と根拠

ORDレコード
ord-ed13e4fbd0e04456abf196e0fa07a951
出典データセット
uspto-grants-1991_02
特許番号
US04990510

反応ノート

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