Thionyl Chloride → Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro-

HRID 981361

反応式

HRID 981361 の反応式
[Cl:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[C:9]([Cl:14])[C:8]([F:15])=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:18])=O>CN(C)C=O>[Cl:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[C:9]([Cl:14])[C:8]([F:15])=[CH:7][C:3]=1[C:4]([Cl:18])=[O:5]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 27342592,4-Dichloro-5-fluoro-3-nitrobenzoic acid

生成物 1

HCID 11818130Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro-

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide触媒

実験手順

254 g (1 mol) of 2,4-dichloro-5-fluoro-3-nitro-benzoic acid are refluxed in 700 ml of thionyl chloride with addition of 3 drops of dimethylformamide until the gas evolution ceases. Excess thionyl chloride is removed by distillation, and the residue is fractionated in vacuo.

後処理

  1. customExcess thionyl chloride is removed by distillation

出典と根拠

ORDレコード
ord-6e9702b552f34a4487227e7863837c8d
出典データセット
uspto-grants-1991_02
特許番号
US04990661

関連ノート

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