Water → HCID 20068349、化合物

HRID 981861

反応式

HRID 981861 の反応式
[NH2:1][C:2]1[C:7]([CH3:8])=[C:6]([NH2:9])[CH:5]=[CH:4][C:3]=1[CH3:10].Cl[C:12]1[C:17]([N+:18]([O-])=O)=[CH:16][CH:15]=[CH:14][N:13]=1.C(=O)([O-])[O-:22].[Ca+2].[OH2:26]>>[N+:1]([C:2]1[C:7]([CH3:8])=[C:6]([NH:9][C:12]2[C:17]([NH2:18])=[CH:16][CH:15]=[CH:14][N:13]=2)[CH:5]=[CH:4][C:3]=1[CH3:10])([O-:22])=[O:26]

参加物

5

反応物 4

HCID 962WaterHCID 10112Calcium CarbonateHCID 796132-Chloro-3-nitropyridineHCID 46255812,4-Dimethylbenzene-1,3-diamine

生成物 1

HCID 20068349HCID 20068349、化合物

反応条件

温度
20 °C

実験手順

8.4 g of 2,4-diamino-m-xylene, 9.6 g of 2-chloro-3nitropyridine and 3.0 g of calcium carbonate were introduced into 300 ml water and the resulting mixture was heated under reflux for 8 hours to the boiling temperature. The reaction mixture was filtered while hot, the reaction product precipitating from the filtrate on cooling to 20° C. It was isolated and recrystallized from toluene. 6.2 g of the product melting at 173° to 175° C. were obtained.

後処理

  1. temperaturethe resulting mixture was heated
  2. temperatureunder reflux for 8 hours to the boiling temperature
  3. filtrationThe reaction mixture was filtered while hot, the reaction product
  4. customprecipitating from the filtrate
  5. customIt was isolated
  6. customrecrystallized from toluene

出典と根拠

ORDレコード
ord-83d842d100b547959c007af42c3def27
出典データセット
uspto-grants-1991_02
特許番号
US04994087

関連ノート

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